BEFORE ACCESSING THIS SITE, PLEASE READ THE FOLLOWING TERMS AND CONDITIONS CAREFULLY AS THEY GOVERN YOUR USE OF THIS SITE. IF YOU DO NOT AGREE WITH THESE TERMS AND CONDITIONS, YOU ARE NOT GRANTED PERMISSION BY ADOLOR CORPORATION TO ACCESS OR OTHERWISE USE THIS SITE. YOU SHOULD REVIEW THESE TERMS AND CONDITIONS REGULARLY AS THEY MAY CHANGE AT ANY TIME AT OUR SOLE DISCRETION.

ADOLOR.COM User Agreement
Welcome to the Adolor Corporation website, also referred to as "Site," owned and operated by Adolor Corporation, also referred to as "Adolor" "us" or "we." This Agreement contains the terms, covenants, conditions, and provisions (the "Terms and Conditions") upon which you ("You") may access and use this Site.

Terms and Conditions
By accessing, viewing, or using this Site, You, the user, indicate that You understand and intend these Terms and Conditions to be the legal equivalent of a signed, written contract and equally binding, and that You accept such Terms and Conditions and agree to be legally bound by them. Please note that Adolor reserves the right to change these Terms and Conditions. Your continued use of this Site following such modifications will be conclusively deemed acceptance of any changes to these Terms and Conditions.

License Grant
This Agreement provides You with a personal, revocable, nonexclusive, nontransferable license to use this Site conditioned on Your continued compliance with the Terms and Conditions of this Agreement. You may print and download materials and information on this Site solely for personal and noncommercial use, provided that all hard copies contain all copyright and other applicable notices contained in such materials and information. As a further condition of use of this Site, You warrant to Adolor that You will not use this Site for any purpose that is unlawful or otherwise prohibited by these Terms and Conditions.

Intellectual Property Rights
All materials contained in the Site are protected by law, including but not limited to United States copyright, trade secret, and trademark law, as well as other state, national, and international laws and regulations. The contents of and all materials distributed in conjunction with the Site are Copyright (c)2004 Adolor Corporation or its licensors or suppliers, all rights reserved. Adolor also owns a copyright in the Site as a collective work and/or compilation, and in the selection, coordination, arrangement, and enhancement of such content. Republication or citation of any other content generated by the Site without Adolor' s written consent is expressly prohibited. You agree not to copy, modify, adapt, frame, mirror, reproduce, translate, distribute, transmit, reverse engineer, decompile, or disassemble any aspect of the Site, except as expressly allowed by this Agreement. All product names, whether or not appearing in large print, italics or with the trademark symbol, are trademarks of Adolor Corporation, its affiliates, related companies or its licensors or collaboration partners and any use of such marks without the express written permission of Adolor is strictly prohibited. Unauthorized use of any material contained on this Site may violate copyright laws, trademark laws, trade secret laws, the laws of privacy and publicity, and communications regulations and statutes. Please be aware that Adolor actively and aggressively enforces its intellectual property rights to the fullest extent of the law.

Copyright Owners' Rights Under the Digital Millennium Copyright Act Of 1998
The Digital Millennium Copyright Act of 1998 (the "DMCA") provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under US copyright law. If You believe in good faith that materials hosted by Adolor infringe Your copyright, You (or Your agent) may send us a notice requesting that the materials be removed, or access to them blocked. If You believe in good faith that a notice of copyright infringement has been wrongly filed against You, the DMCA permits You to send us a counter-notice.

Notices and counter-notices must meet statutory requirements imposed by the DMCA. One place to find more information on the DMCA is the U.S. Copyright Office website. Notices and counter-notices for the Site should be sent to Martha E. Manning, Esq., General Counsel, Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341.

Submissions
Adolor welcomes Your feedback and suggestions about how to improve this Site. Any ideas, suggestions, information, know-how, material, or other content (collectively, "content") received through this Site, however, will be deemed to include a royalty-free, perpetual, irrevocable, transferable, worldwide, nonexclusive right and license for Adolor to adopt, publish, reproduce, disseminate, transmit, distribute, copy, use, create derivative works, display, (in whole or part), or act on such content without additional approval or consideration, in any form, media, or technology now known or later developed for the full term of any rights that may exist in such content.

If You transmit to or post on our Site any material, data, information or idea by any means, it will be treated as non-confidential and non-proprietary and may be disseminated or used by us for any purpose.

You are not authorized to post on or transmit to or from our Site any unlawful, threatening, libelous, defamatory, obscene, scandalous, inflammatory, pornographic, or profane material, or any other content that could give rise to any civil or criminal liability under the law.

Jurisdiction
The information provided on this Site is intended for U.S. audiences and has been designed to comply with U.S. regulatory guidelines.

Disclaimer
The content of this Adolor website is provided "As Is" and Adolor Corporation makes no representations or warranties of any kind, whether express or implied, created by law, contract or otherwise, including, but not limited to any warranties of merchantability, fitness for a particular purpose, title, or non-infringement. While Adolor makes reasonable efforts to ensure the timeliness and accuracy of the materials present on this website, its makes no assurances or warranties as to the accuracy of the information provided on this website and shall not be liable for any direct, indirect, incidental, consequential or otherwise special damages or injuries resulting from the use of this website and reliance on the materials contained here. Adolor may make changes to these materials at any time, without notice, and makes no representation or warranty that access to the website will be available on a continuous basis, will be uninterrupted or that the information contained on the website will be timely, complete or error free. Each user assumes full responsibility and all risks arising from access to and use of this website.

Medical Information/Conditions
Medical information that appears on this website is for informational purposes only and is not, nor is intended to be, a medical diagnosis or a replacement for advice given by a physician or other medical professional. Any reliance on the information provided on this website is solely the responsibility of the individual. Adolor undertakes no commitment to update the information contained in the Site.

Links to Other Websites
This website may link You to other websites that are not owned or controlled by Adolor Corporation. We reserve the right to terminate a link to a third party website at any time. The fact that we provide a link to a third party website does not mean that we endorse, authorize or sponsor that website. It also does not mean that we are affiliated with the third party website's owners or sponsors. These links are provided for Your convenience only. These sites are maintained by entities over which Adolor Corporation exercises no control. Accordingly, Adolor Corporation expressly disclaims any responsibility for the content, the accuracy of the information and/or quality of products or services provided by or advertised on these third-party sites. If You choose to hyperlink to another website, You do so at Your own risk.

Links from Other Web Sites to Our Site
If a third party links to our Site, it is not necessarily an indication of an endorsement, authorization, sponsorship, affiliation, joint venture or partnership by or with us. In most cases, we are not aware that a third party has linked to our Site.

We Are Not Providing Investment Advice Nor Soliciting Offers
Nothing in this site constitutes investment advice, including our SEC filings. We provide investor relations materials for Your convenience and information only. In addition, investor relations materials and our other Site content are not offers to sell or solicitations of an offer to buy any security.

There are no guarantees about the future performance of the stock market or our stock. Before You invest in any security, You can protect Yourself by being an educated investor. If You are interested in our stock, we recommend that, at a minimum, You read our latest annual report and 10-K, 10-Q and 8-K reports to the SEC over the past year. Our recent proxy statements for shareholder meetings also contain important information. It is also advisable to learn more about us and our industry through a variety of public materials.

Our recent annual reports, 10-K and 10-Q reports and other materials are accessible through this Site. Other materials we have filed with the SEC are available through its website at http://www.sec.gov. You can also visit the SEC at its Washington or various regional offices for the same information or hire a document retrieval service to obtain the filings for You.

You Should Not Rely on the Stock Price Information on Our Website
We do not generate the information regarding Adolor Corporation stock prices for our Site. We believe the information on the stock price is accurate, but we cannot guarantee or warrant the accuracy, completeness, or timeliness of the information. You should not rely on the stock price information for investment purposes. We are not liable for any loss or damages, whether direct, indirect, incidental, special, consequential, or exemplary, that arise from reliance on information on the stock price on our website.

You Should Not Rely on the E Mail Alert Service Available Through Our Website
The E-Mail Alert Service available through our Website is provided through a third party and we cannot guarantee or warrant the accuracy, completeness or timeliness of the E-Mail Alert Service. You should not rely on this service for investment purposes. We are not liable for any loss or damages, whether direct, indirect, incidental, special, consequential, or exemplary, that arise from reliance on the E-Mail Alert Service available through our website.

Forward Looking Statement
Various statements made in this Website are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include those which express plan, anticipation, intent, contingency, goals, targets or future development and/or otherwise are not statements of historical fact. We have based these forward-looking statements on our current expectations and projections about future events and they are subject to risks and uncertainties known and unknown which could cause actual results and developments to differ materially from those expressed or implied in such statements. These forward-looking statements include statements about the following:

• our product development efforts, including results from clinical trials;
• anticipated dates of clinical trial initiation, completion and announcement of trial results;
• anticipated trial results and regulatory filing dates for our product candidates;
• the status and anticipated timing of regulatory approval, if any, for our product candidates;
• analysis and interpretation of data by regulatory authorities;
• anticipated operating losses and capital expenditures;
• our intentions regarding the establishment of collaborations;
• anticipated efforts of our collaborators;
• estimates of the market opportunity and the commercialization plans for our product candidates, including our plans for the development of a sales force;
• our intention to rely on third parties for manufacturing;
• our ability to raise additional capital; and
• our ability to acquire or in-license products or product candidates.

In some cases, You can identify forward-looking statements by terminology such as "may," "will," "should," "could," "would," "expect," "plan," "anticipate," "believe," "estimate," "target," "goal," "continue," or the negative of such terms or other similar expressions. Adolor Corporation's performance and financial results could differ materially from those reflected in these forward-looking statements due to general financial, economic, regulatory and political conditions affecting the biotechnology and pharmaceutical industries as well as more specific risks and uncertainties such as those set forth in its reports on Form 8-K, 10-Q and 10-K filed with the U.S. Securities and Exchange Commission ("SEC").

We urge You to carefully review and consider the disclosures found in these SEC filings, all of which are available in the SEC EDGAR database at www.sec.gov. Given the uncertainties affecting pharmaceutical companies in the development stage, You are cautioned not to place undue reliance on any such forward-looking statements, any of which may turn out to be wrong due to inaccurate assumptions, unknown risks, uncertainties or other factors. Adolor Corporation undertakes no obligation to (and expressly disclaim any such obligation to) publicly update or revise the statements made herein or the risk factors that may relate thereto whether as a result of new information, future events or otherwise.

Privacy Statement
Adolor is committed to protecting the privacy of individuals visiting its website. However, Adolor does not render health care services and is not a health care provider. The Site does not utilize "cookies" that would allow Adolor to remember information about You or Your preferences. If You choose to submit information that could be considered personal in nature, it will be treated as non-confidential and non-proprietary information by Adolor and the company shall have no obligations of any kind with respect to such information except such obligations as may be required by Federal and state law.

Miscellaneous
Our failure to insist upon or enforce strict performance of any provision of this Agreement shall not be construed as a waiver of any provision or right. Neither the course of conduct between the parties nor trade practice shall act to modify any provision of this Agreement. We may assign our rights and duties under this Agreement to any party at any time without notice to You.